Appropriation is the mother of invention

Necessity is the mother of invention.

A well executed transseptal puncture is crucial for successful percutaneous transvenous mitral balloon valvotomy. We report a case of accidentally damaged Mullins sheath dilator. Due to immediate unavailability of another dilator at cardiac catheterization laboratory, angioplasty guidewire and balloon was used as an additional assisting armamentarium for successful percutaneous transvenous mitr...

Agricultural innovation—necessity is the mother of invention

Innovation is the process leading to the adoption of new or existing information, technology or practices; it includes factors that affect demand for and use of knowledge in novel and useful ways. In agriculture, innovation is essential to maintain productivity growth, to address issues around sustaining the natural resource base and to adapt to climate change. This paper examines the innovatio...

How is the Mother Tongue Acquired

Muscular dystrophy meets protein biochemistry, the mother of invention.

Muscular dystrophies result from a defect in the linkage between the muscle fiber cytoskeleton and the basement membrane (BM). Congenital muscular dystrophy type MDC1A is caused by mutations in laminin α2 that either reduce its expression or impair its ability to polymerize within the muscle fiber BM. Defects in this BM lead to muscle fiber damage from the force of contraction. In this issue of...

Necessity is the mother of invention: a simple grid computing system using commodity tools

Access to sufficient resources is a barrier to scientific progress for many researchers facing large computational problems. Gaining access to large-scale resources (i.e., university-wide or federally supported computer centers) can be difficult, given their limited availability, particular architectures, and request/review/approval cycles. Simultaneously, researchers often find themselves with...